LaPlace was settled as a farming village in the 18th century during Louisiana's French colonial era. It was named after early settler Basile LaPlace.

The city's railroad station was established in 1883.

LaPlace was the birthplace of early jazz musicians Kid Ory and Wellman Braud.

LaPlace has been designated "Andouille Capital of the World." An Andouille Festival is held every year in October.

Basile Laplace spelled his name with a small, not capital "p".

LaPlace is a census-designated place (CDP) in St. John the Baptist Parish, Louisiana, United States, along the east bank of the Mississippi River in the New Orleans metropolitan area. The population was 27,684 at the 2000 census.

LaPlace is the southern terminus of Interstate 55, where it joins with Interstate 10, and of US 51, where it terminates at the junction with US 61. LaPlace is located 25 miles (40 kilometers) west of New Orleans.

The nickname is "Andouille Capital of the World" (for the food).